Arms                    Class of Arm
Controllers             Class of Controller
CorrelatedPfsAndOs2     Generate Correlated PFS and OS Using Gumbel
                        Copula
CorrelatedPfsAndOs3     Generate Correlated PFS and OS Using the
                        Three-States Illness-Death Model
CorrelatedPfsAndOs4     Generate Correlated PFS, OS and Objective
                        Response
DynamicRNGFunction      A wrapper of random number generator.
Endpoints               Class of Endpoint
GraphicalTesting        Class of GraphicalTesting
GroupSequentialTest     Class of GroupSequentialTest
Listeners               Class of Listener
Milestones              Class of Milestones
PiecewiseConstantExponentialRNG
                        Generate Time-to-Event Endpoint from Piecewise
                        Constant Exponential Distribution
Regimens                Class of Regimens
StaggeredRecruiter      Generate Enrollment Time from Piecewise
                        Constant Uniform Distribution
Trials                  Class of Trial
add_arms                Adding One or More Arms to a Trial
arm                     Define an Arm
calendarTime            Triggering Condition by Calendar Time
controller              Define a Controller
crossover               Crossover at a Milestone
doNothing               An Action Function that Does Nothing
endpoint                Define Endpoints
enrollment              Triggering Condition by Number of Randomized
                        Patients
eventNumber             Triggering Condition by Number of Events or
                        Non-missing Observations of an Endpoint
expandRegimen           Expand regimen trajectory into long format
fitCoxph                Fit Cox Proportional Hazard Ratio model
fitFarringtonManning    Farrington-Manning test for rate difference
fitLinear               Fit linear regression model
fitLogistic             Fit logistic regression model
fitLogrank              Carry out log rank test
getAdaptiveDesignOutput
                        Get simulation output in the vignette
                        adaptiveDesign.Rmd
getDoseRangingOutput    Get simulation output in the vignette
                        doseRanging.Rmd
getFixedDesignOutput    Get simulation output in the vignette
                        fixedDesign.Rmd
listener                Define a Listener
milestone               Define a Milestone
plot.milestone_time_summary
                        Plot Triggering Time of Milestones in Simulated
                        Trials
plot.three_state_model
                        Plot result of three-state illness-death model
qPiecewiseExponential   Quantile Function of Piecewise Exponential
                        Distribution
rconst                  Generate Constant Variable
regimen                 Define a Regimen
remove_arms             Removing One or More Arms From a Trial
resize                  Resizing a Trial
set_duration            Extending Duration of a Trial
solveMixtureExponentialDistribution
                        Solve Parameters in a Mixture Exponential
                        Distribution
solvePiecewiseConstantExponentialDistribution
                        Compute Constant Rates of Piecewise Exponential
                        Distribution
solveThreeStateModel    Solve Parameters in a Three-State Illness-death
                        Model
summarizeDataFrame      Summarize A Data Frame
summarizeMilestoneTime
                        Summary of Milestone Time from Simulated Trials
trial                   Define a Trial
update_generator        Updating Data Generators of One or More
                        Endpoints in an Arm
update_sample_ratio     Updating Sampling Ratios of Existing Arms in a
                        Trial
weibullDropout          Calculate Parameters of Weibull Distribution as
                        a Dropout Method
