Package: ondisc
Title: Algorithms and Data Structures for Large Single-Cell Expression
        Matrices
Version: 1.3.5
Depends: R (>= 4.1.0)
Authors@R: 
    c(person(given = "Timothy",
            family = "Barry",
            role = c("aut", "cre"),
            email = "tbarry@hsph.harvard.edu",
            comment=c(ORCID="0000-0002-4356-627X")),
      person(given = "Songcheng",
             family = "Dai",
             role = "ctb"),
      person(given = "Yixuan",
             family = "Qiu",
             role = "ctb"),
      person(given = "Eugene",
            family = "Katsevich",
            role = c("aut", "ths"),
            email = "ekatsevi@wharton.upenn.edu"))
Description: Single-cell datasets are growing in size, posing challenges
    as well as opportunities for genomics researchers. 'ondisc' is an R
    package that facilitates analysis of large-scale single-cell data
    out-of-core on a laptop or distributed across tens to hundreds of
    processors on a cluster or cloud. In both of these settings, 'ondisc'
    requires only a few gigabytes of memory, even if the input data are tens
    of gigabytes in size. 'ondisc' mainly is oriented toward single-cell
    CRISPR screen analysis, but also can be used for single-cell differential
    expression and single-cell co-expression analyses. 'ondisc' is powered by
    several new, efficient algorithms for manipulating and querying large,
    sparse expression matrices.
License: MIT + file LICENSE
Encoding: UTF-8
LinkingTo: Rcpp, Rhdf5lib
biocViews: DataImport, SingleCell, DifferentialExpression, CRISPR
RoxygenNote: 7.3.2
Imports: crayon, data.table, methods, Rcpp, Rhdf5lib, dplyr, readr,
        Matrix
SystemRequirements: GNU make
Suggests: sessioninfo, knitr, R.utils, rmarkdown, testthat (>= 3.0.0)
Config/testthat/edition: 3
URL: https://timothy-barry.github.io/ondisc/,
        https://timothy-barry.github.io/sceptre-book/
BugReports: https://github.com/timothy-barry/ondisc/issues
VignetteBuilder: knitr
NeedsCompilation: yes
Packaged: 2026-06-09 16:49:18 UTC; timbarry
Author: Timothy Barry [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-4356-627X>),
  Songcheng Dai [ctb],
  Yixuan Qiu [ctb],
  Eugene Katsevich [aut, ths]
Maintainer: Timothy Barry <tbarry@hsph.harvard.edu>
Repository: CRAN
Date/Publication: 2026-06-17 13:30:02 UTC
Built: R 4.6.1; x86_64-w64-mingw32; 2026-08-23 03:41:23 UTC; windows
Archs: x64
